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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T60047 | V-0219 | Glucagon Receptor | |
V-0219 is a positive allosteric modulator of GLP-1 and can be used in studies about obesity-associated diabetes. | |||
T60047L | V-0219 hydrochloride | V-0219 hydrochloride(878453-71-5 Free base) | Glucagon Receptor |
V-0219 hydrochloride, an orally-active positive allosteric modulator (PAM) of the glucagon-like peptide-1 receptor (GLP-1R), is utilized in obesity-associated diabetes research. | |||
T3283 | Cetilistat | ATL-962 | Lipid |
Cetilistat (ATL-962) is a novel inhibitor of pancreatic lipase being developed by Alizyme for the treatment of obesity and associated co-morbidities, including type 2 diabetes. | |||
T4723 | D-Tagatose | D-(-)-Tagatose,d-tagatos | Others , Endogenous Metabolite |
D-Tagatose (D-(-)-Tagatose), a rare natural hexoketose, is an isomer of d-galactose. D-Tagatose occurs naturally in Sterculia setigera gum, and it is also found in small quantities in various foods such as sterilized and... | |||
T39488 | Relzomostat | ||
Relzomostat is a MetAP2 inhibitor, specifically targeting methionine aminopeptidase 2. It holds potential in research concerning obesity, type 2 diabetes, and other conditions associated with obesity. | |||
T40950 | A3334 | ||
A3051, is a robust and orally active inhibitor of CXXC5-DVL with an IC 50 of 63.06 nM. Its applications include research into phenotypes associated with obesity, diabetes, and NASH that are induced by high fat diet (HFD)... | |||
T81628 | OB3 | ||
OB3, a leptin derivative, exhibits greater efficacy than leptin in diminishing obesity and diabetes in mouse models. Additionally, OB3 mitigates leptin-associated inflammation and proliferation in hepatocellular carcinom... | |||
T74672 | Sirtuin modulator 5 | ||
Sirtuin Modulator 5, a sirtuin modulating agent, activates SIRT1 with an efficacy marked by a DC50 value of less than 50 μM. It is applicable in enhancing cell longevity and is researched for its therapeutic potential in... |